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Title : Anatomic features vs pathology vs molecular stratification
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Anatomic features vs pathology vs molecular stratification

Found this interesting article - and even though it is quite old (2008) and only involves a small cohort of AA3 patients for it´s statistics, I still found it interesting.

In most, especially recent, articles the main focus is on either pathology (mitosis count, proliferative index etc) or on molecular constitution of the tumors - or at least the combination.

This article is interesting because it also focusses on the anatomy of the tumors - particular enhancement and - even more important - resection degree and growth pattern of the tumor.

And if you look at survival statistics - even though from a small cohort - in the article there seems to be quite some interesting viewports in analysis of the anatomy of the tumors.

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jmri.21593 

This article was of course before the WHO 2016 definitions and it doesn´t concern itself with the further diomensions of e.g. IDH, methylation ATRX etc. That would probably add some explanation to some of the quite dramatic differences in OS in the cohort.

Any thoughts on this aspect of tumor anatomy or other interesting studies to the subject?

Thus Article Anatomic features vs pathology vs molecular stratification

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