Title : Chapter 7: The Great Risks of 5G: What We Know and What We Don’t Know
link : Chapter 7: The Great Risks of 5G: What We Know and What We Don’t Know
Chapter 7: The Great Risks of 5G: What We Know and What We Don’t Know
Chapter 7: The Great Risks of 5G: What We Know and What We Don’t Know
We have already discussed two issues that are essential to understanding 5G. One is that pulsed EMFs are, in most cases, much more biologically active than are non-pulsed (often called
We have already discussed two issues that are essential to understanding 5G. One is that pulsed EMFs are, in most cases, much more biologically active than are non-pulsed (often called
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continuous wave) EMFs. A second is that the EMFs act by putting forces on the voltage sensor of the VGCCs, opening these calcium channels and
allowing excessive calcium ions to flow into the cell. The voltage sensor is extraordinarily sensitive to those electrical forces, such that the safety guidelines are allowing us to be exposed to EMFs that are something like 7.2 million times too high.The reason that the industry has decided to go to the extremely high frequencies of 5G is that with such extremely high frequencies, it is possible to carry much more information via much more pulsation than it is possible to carry with lower frequencies even in the microwave range. We can be assured, therefore, that 5G will involve vastly more pulsation than do EMFs that we are currently exposed to. It follows from that, that any biological safety test of 5G must use the very rapid pulsations including whatever very short term spikes may be present, that are to be present in genuine 5G. There is an additional process that is planned to be used in 5G: phased arrays (https://ift.tt/1E0OLyk). Here multiple antenna elements act together to produce highly pulsed fields which are designed for 5G, to produce increased penetration. 5G will entail particularly powerful pulsations to be used, which may, therefore, be particularly hazardous.
The only data we have, to my knowledge, on millimeter wave frequencies of 5G used non-pulsed EMFs in the millimeter frequency range of 5G, not genuine 5G. Such millimeter waves have been shown to produce a number of downstream effects of VGCC activation. One millimeter wave study showed that it activated both the VGCCs and also the voltage-gated potassium channels, suggesting that it worked via the voltage sensor, as do other EMFs [136]. Any such data tells us almost nothing about how biologically active genuine very highly pulsed 5G will be. I take it that from their statements, that both Mr. Ryan and Dr. Vinciūnas are ready to put out 10s of millions of 5G antennae to afflict every single person in the EU with 5G radiation without even a single biological test of safety of genuine 5G. In the U.S., the FCC has taken a much worse position. The FCC is not only willing to allow such completely untested exposures but has also been has been aggressively pushing to promote installation of 5G antennae, such that antennae are already being installed in parts of the U.S. In a world where shocking behavior has become less and less shocking, I consider EU and U.S. views and actions to be shocking. The U.S. situation is mass insanity. I would have hoped that the Europeans, who think of themselves as being much more thoughtful than Americans, would have been genuinely more thoughtful.
Why does 5G need such high numbers of antennae? It is because the 5G radiation is much more absorbed as it enters various materials. The approach is to use many more antennae with one found every few houses, such that 5G can sufficiently penetrate local walls. Such absorption usually involves the interaction with electrically charged groups, such that such high absorption is likely to involve placing forces on electrically charged groups. Because such forces are the way in which EMFs activate the VGCCs, it seems highly likely, therefore, that 5G radiation will be particularly active in VGCC activation.
In summary, then, 5G is predicted to be particularly dangerous for each of four different reasons: 1. The extraordinarily high numbers of antennae that are planned. 2. The very high energy outputs which will be used to ensure penetration. 3. The extraordinarily high pulsation levels. 4. The apparent high level interactions of the 5G frequency on charged groups presumably including the voltage sensor charged groups.
Now what the telecommunications industry argues is that 5G radiation will be mostly absorbed in the outer 1 or 2 mm of the body, such that they claim that we don’t have to worry about the effects. There is some truth to that, but there are also some caveats that make any conclusions
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made from that, much more suspect. In any case, these surface effects of 5G will have especially strong impact on organisms with much higher surface to volume ratios. Consequently, I predict that many organisms will be much more impacted than we will. This includes insects and other arthropods, birds and small mammals and amphibia. It includes plants including even large trees, because trees have leaves and reproductive organs that are highly exposed. I predict there will be major ecological disasters as a consequence of 5G. This will include vast conflagrations because EMF exposures make plants much more flammable.
But let’s get back to humans. The industry has also made claims that more conventional microwave frequency EMFs are limited in effect to the outer 1 cm of the body. We know that is not true, however because of the effects deep in the human brain, on the heart and on hormone systems. Perhaps the most important two studies demonstrating effects deep within the body are the studies of Professor Hässig and his colleagues in Switzerland on cataract formation in newborn calves [137,138]. These two studies clearly show that when pregnant cows are grazing near mobile phone base stations (also called cell phone towers), the calves are born with very greatly increased incidences of cataracts. It follows from these findings that even though the developing fetuses are very deep in the body of the mother and should be highly protected from the EMF exposures, they are not so protected. And because the EMF safety guidelines in Switzerland are 100 times more stringent than are the safety guidelines in most of the rest of Europe, in the U.S., Canada and most of the rest of the world, the more general safety guidelines allow greatly excessive exposures and penetration of effects. The claims of industry that microwave frequency EMFs only act in the outer centimeter of the body are clearly false.
How then can both conventional microwave frequency EMFs and 5G radiation act deeply within the body? You may correctly observe that the electrical effects of the EMFs activate the voltage sensor and that the direct electrical forces are rapidly attenuated in the body. So how can we get deep effects? I think the answer is that the magnetic parts of the EMFs have been known for decades to penetrate much more deeply than do the electrical parts. The magnetic fields put forces on mobile electrically charged groups dissolved in the aqueous phases of the body and small individual movements of the charged groups can regenerate electric fields that are essentially identical to the electric fields of the original EMFs, carrying the same frequency and same pulsation pattern, although with lower intensity. An example of this is given in the Lu and Ueno [139] study. Because the voltage sensor is so stunningly sensitive to electrical forces and part of the reason for that is the very high level of amplification of the electrical field across the plasma membrane, we have an almost perfect way in which to produce EMF effects deeply within our bodies.
I am very concerned that 5G may produce effects like those we already see produced from lower frequency EMFs but are much more severe. I am also concerned that we will also see responses that are qualitatively different. Let me give you three possible examples of the latter type and one quantitative example. Each of the four types of blindness, have downstream effects of VGCC activation as causal factors: cataracts, detached retinas, glaucoma and macular degeneration. The aqueous and vitreous humors in the eye may be an ideal environment for the regeneration of the electrical fields within the eye. We may, therefore have a gigantic epidemic of each of the four types of blindness. Another concern focuses on kidney dysfunction, which was shown in Chapter 5 to be impacted by EMFs. The kidneys have much fluid, both blood and also what will become urine, which may allow efficient the regeneration of electrical fields. Such regeneration may be expected to impact both the glomerular filtration and also the reabsorption, both essential to kidney function. Does this mean that 5G will produce very large increases in kidney failure? The only way to find out is to do biological safety testing of genuine 5G radiation. Let me give you a third example. Fetuses and very young babies have much more water in their bodies than do
But let’s get back to humans. The industry has also made claims that more conventional microwave frequency EMFs are limited in effect to the outer 1 cm of the body. We know that is not true, however because of the effects deep in the human brain, on the heart and on hormone systems. Perhaps the most important two studies demonstrating effects deep within the body are the studies of Professor Hässig and his colleagues in Switzerland on cataract formation in newborn calves [137,138]. These two studies clearly show that when pregnant cows are grazing near mobile phone base stations (also called cell phone towers), the calves are born with very greatly increased incidences of cataracts. It follows from these findings that even though the developing fetuses are very deep in the body of the mother and should be highly protected from the EMF exposures, they are not so protected. And because the EMF safety guidelines in Switzerland are 100 times more stringent than are the safety guidelines in most of the rest of Europe, in the U.S., Canada and most of the rest of the world, the more general safety guidelines allow greatly excessive exposures and penetration of effects. The claims of industry that microwave frequency EMFs only act in the outer centimeter of the body are clearly false.
How then can both conventional microwave frequency EMFs and 5G radiation act deeply within the body? You may correctly observe that the electrical effects of the EMFs activate the voltage sensor and that the direct electrical forces are rapidly attenuated in the body. So how can we get deep effects? I think the answer is that the magnetic parts of the EMFs have been known for decades to penetrate much more deeply than do the electrical parts. The magnetic fields put forces on mobile electrically charged groups dissolved in the aqueous phases of the body and small individual movements of the charged groups can regenerate electric fields that are essentially identical to the electric fields of the original EMFs, carrying the same frequency and same pulsation pattern, although with lower intensity. An example of this is given in the Lu and Ueno [139] study. Because the voltage sensor is so stunningly sensitive to electrical forces and part of the reason for that is the very high level of amplification of the electrical field across the plasma membrane, we have an almost perfect way in which to produce EMF effects deeply within our bodies.
I am very concerned that 5G may produce effects like those we already see produced from lower frequency EMFs but are much more severe. I am also concerned that we will also see responses that are qualitatively different. Let me give you three possible examples of the latter type and one quantitative example. Each of the four types of blindness, have downstream effects of VGCC activation as causal factors: cataracts, detached retinas, glaucoma and macular degeneration. The aqueous and vitreous humors in the eye may be an ideal environment for the regeneration of the electrical fields within the eye. We may, therefore have a gigantic epidemic of each of the four types of blindness. Another concern focuses on kidney dysfunction, which was shown in Chapter 5 to be impacted by EMFs. The kidneys have much fluid, both blood and also what will become urine, which may allow efficient the regeneration of electrical fields. Such regeneration may be expected to impact both the glomerular filtration and also the reabsorption, both essential to kidney function. Does this mean that 5G will produce very large increases in kidney failure? The only way to find out is to do biological safety testing of genuine 5G radiation. Let me give you a third example. Fetuses and very young babies have much more water in their bodies than do
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adults. Therefore, they may be a special risk for impacts of 5G, because of great increases in the regeneration of the electrical fields. Here one can think of all kinds of possibilities. Let me suggest two. We may have a gigantic (sorry about using that word again) epidemic of spontaneous abortion due the teratogenic effects. Another possibility is that instead of autism being one birth in 38, however horrendous that is, it could be one out of two, or even a majority of births. I don’t know that these will happen, but these are the kinds of risks we are taking and there are many others one can think of. Putting in tens of millions of 5G antennae without a single biological test of safety has got to be about the stupidest idea anyone has had in the history of the world.
This brings us back to the earlier point. The only way to do 5G safety testing is to do genuine 5G biological safety testing. I have published on how this can be done relatively easily at relatively low cost and have, as you saw in the Chapter 6, told the FCC how this can be done. Those tests must be done by organizations completely independent of industry and that leaves out both ICNIRP and SCENIHR and a lot of other organizations.
Now we will get into the precautionary principle which is specially relevant to the EU but may have lessons for all of us.
Dr. Vinciūnas’ last full paragraph reads as follows: “The recourse to the EU’s precautionary principle to stop distribution of 5G products appears too drastic a measure. We need first to see how this technology will be applied and how the scientific evidence will evolve. Please be assured that the Commission will keep abreast of the scientific evidence in view of safeguarding the health of European citizens at the highest level possible and in line with its mandate.”
Article 191 defines the Precautionary Principle as follows:
“According to the European Commission the precautionary principle may be invoked when a phenomenon, product or process may have a dangerous effect, identified by a scientific and objective evaluation, if this evaluation does not allow the risk to be determined with sufficient certainty.
Recourse to the principle belongs in the general framework of risk analysis (which, besides risk evaluation, includes risk management and risk communication), and more particularly in the context of risk management which corresponds to the decision-making phase.
The Commission stresses that the precautionary principle may only be invoked in the event of a potential risk and that it can never justify arbitrary decisions.
The precautionary principle may only be invoked when the three preliminary conditions are met:
identification of potentially adverse effects; evaluation of the scientific data available; the extent of scientific uncertainty.”
The question now is what about 5G? We have with 5G strong suspicions of similar or much more severe risk of effects documented elsewhere in this document. We have no biological safety testing of genuine 5G radiation. Therefore, we have no risk analysis or risk management because we have no risk assessment whatsoever on 5G. So here we have Dr. Vinciūnas arguing that the request for precautionary principle application is premature. But it is not the request for
This brings us back to the earlier point. The only way to do 5G safety testing is to do genuine 5G biological safety testing. I have published on how this can be done relatively easily at relatively low cost and have, as you saw in the Chapter 6, told the FCC how this can be done. Those tests must be done by organizations completely independent of industry and that leaves out both ICNIRP and SCENIHR and a lot of other organizations.
Now we will get into the precautionary principle which is specially relevant to the EU but may have lessons for all of us.
Dr. Vinciūnas’ last full paragraph reads as follows: “The recourse to the EU’s precautionary principle to stop distribution of 5G products appears too drastic a measure. We need first to see how this technology will be applied and how the scientific evidence will evolve. Please be assured that the Commission will keep abreast of the scientific evidence in view of safeguarding the health of European citizens at the highest level possible and in line with its mandate.”
Article 191 defines the Precautionary Principle as follows:
“According to the European Commission the precautionary principle may be invoked when a phenomenon, product or process may have a dangerous effect, identified by a scientific and objective evaluation, if this evaluation does not allow the risk to be determined with sufficient certainty.
Recourse to the principle belongs in the general framework of risk analysis (which, besides risk evaluation, includes risk management and risk communication), and more particularly in the context of risk management which corresponds to the decision-making phase.
The Commission stresses that the precautionary principle may only be invoked in the event of a potential risk and that it can never justify arbitrary decisions.
The precautionary principle may only be invoked when the three preliminary conditions are met:
identification of potentially adverse effects; evaluation of the scientific data available; the extent of scientific uncertainty.”
The question now is what about 5G? We have with 5G strong suspicions of similar or much more severe risk of effects documented elsewhere in this document. We have no biological safety testing of genuine 5G radiation. Therefore, we have no risk analysis or risk management because we have no risk assessment whatsoever on 5G. So here we have Dr. Vinciūnas arguing that the request for precautionary principle application is premature. But it is not the request for
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the use of the precautionary principle that is premature, it is the Commission’s claim that it has done the required risk analysis and risk assessment. This is the bizarre world that we live in.
The European Commission has done nothing to protect European citizens from the very serious health hazards and the U.S. FDA, EPA and National Cancer Institute have done nothing to protect U.S. citizens. The U.S. FCC has been worse than that, acting in wanton disregard for our health.
Let me close, as follows. There have been certain points in our history where people have stood up to strong destructive forces against what often appeared to be insurmountable odds. Those people are THE most honored people in our history. The people who failed to do so are among the most despised people in our history. I am not at all sure we will have historians to record us 100 years from now or even 30 years from now, given the direction in which we are heading. But if we do, rest assured that these are the standards by which we will all be judged.
Citations used in the text:
[1] Levine H, Jorgensen N, Martino-Andrade A, Mendiola J, Weksler-Derri D, Mindlis I, Pinotti R, Swan SH. 2017 Temporal trends in sperm count: a systematic review and meta-analysis. Human Reproduction Update, https://ift.tt/2MZBYD8
[2] Magras IN, Xenos TD. 1997 RF radiation-induced changes in the prenatal development of mice. Bioelectromagnetics 18:455-461.
[3] Pall ML. 2016 Microwave frequency electromagnetic fields (EMFs) produce widespread neuropsychiatric effects including depression. J Chem Neuroanat 75(Pt B):43-51. doi: 10.1016/j.jchemneu.2015.08.001.
[4] Pall, ML. 2013. Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects. J Cell Mol Med 17:958-965. doi: 10.1111/jcmm.12088. [5] Pall, M. L. 2015 Scientific evidence contradicts findings and assumptions of Canadian Safety Panel 6: microwaves act through voltage-gated calcium channel activation to induce biological impacts at non-thermal levels, supporting a paradigm shift for microwave/lower frequency electromagnetic field action. Rev. Environ. Health 3, 99-116. doi: 10.1515/reveh- 2015-0001.
[6] Pall ML. 2016 Electromagnetic fields act similarly in plants as in animals: Probable activation of calcium channels via their voltage sensor. Curr Chem Biol 10: 74-82.
[7] Pall, M. L., 2018. How cancer can be caused by microwave frequency electromagnetic field (EMF) exposures: EMF activation of voltage-gated calcium channels (VGCCs) can cause cancer including tumor promotion, tissue invasion and metastasis via 15 mechanisms. Chapter 7 in Markov, M. S., (Ed.), Mobile Communications and Public Health, CRC Press, Boca Raton, FL, in press.
[8] Belyaev, I., 2005. Non-thermal biological effects of microwaves. Microwave Rev. 11, 13- 29.
[9] Belyaev, I., 2015. Biophysical mechanisms for nonthermal microwave effects. In: Markov M.S. (Ed), Electromagnetic Fields in Biology and Medicine, CRC Press, New York, pp 49-67. [10] Panagopoulos, D. J., Johansson, O., Carlo, G. L., 2015. Polarization: a key difference between man-made and natural electromagnetic fields, in regard to biological activity. Sci. Rep. 2015 Oct 12;5:14914. doi: 10.1038/srep14914.
[11] Pall ML. 2018 Wi-Fi is an important threat to human health. Environ Res 164:405-416. doi: 10.1016/j.envres.2018.01.035.
[12] Pilla, A. A., 2012. Electromagnetic fields instantaneously modulate nitric oxide signaling in challenged biological systems. Biochem. Biophys. Res. Commun. 28, 426:330-333. doi: 10.1016/j.bbrc.2012.08.078.
[13] Lu, X. W., Du, L., Kou, L., Song, N., Zhang, Y. J., Wu, M. K., Shen, J. F., 2015. Effects of
The European Commission has done nothing to protect European citizens from the very serious health hazards and the U.S. FDA, EPA and National Cancer Institute have done nothing to protect U.S. citizens. The U.S. FCC has been worse than that, acting in wanton disregard for our health.
Let me close, as follows. There have been certain points in our history where people have stood up to strong destructive forces against what often appeared to be insurmountable odds. Those people are THE most honored people in our history. The people who failed to do so are among the most despised people in our history. I am not at all sure we will have historians to record us 100 years from now or even 30 years from now, given the direction in which we are heading. But if we do, rest assured that these are the standards by which we will all be judged.
Citations used in the text:
[1] Levine H, Jorgensen N, Martino-Andrade A, Mendiola J, Weksler-Derri D, Mindlis I, Pinotti R, Swan SH. 2017 Temporal trends in sperm count: a systematic review and meta-analysis. Human Reproduction Update, https://ift.tt/2MZBYD8
[2] Magras IN, Xenos TD. 1997 RF radiation-induced changes in the prenatal development of mice. Bioelectromagnetics 18:455-461.
[3] Pall ML. 2016 Microwave frequency electromagnetic fields (EMFs) produce widespread neuropsychiatric effects including depression. J Chem Neuroanat 75(Pt B):43-51. doi: 10.1016/j.jchemneu.2015.08.001.
[4] Pall, ML. 2013. Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects. J Cell Mol Med 17:958-965. doi: 10.1111/jcmm.12088. [5] Pall, M. L. 2015 Scientific evidence contradicts findings and assumptions of Canadian Safety Panel 6: microwaves act through voltage-gated calcium channel activation to induce biological impacts at non-thermal levels, supporting a paradigm shift for microwave/lower frequency electromagnetic field action. Rev. Environ. Health 3, 99-116. doi: 10.1515/reveh- 2015-0001.
[6] Pall ML. 2016 Electromagnetic fields act similarly in plants as in animals: Probable activation of calcium channels via their voltage sensor. Curr Chem Biol 10: 74-82.
[7] Pall, M. L., 2018. How cancer can be caused by microwave frequency electromagnetic field (EMF) exposures: EMF activation of voltage-gated calcium channels (VGCCs) can cause cancer including tumor promotion, tissue invasion and metastasis via 15 mechanisms. Chapter 7 in Markov, M. S., (Ed.), Mobile Communications and Public Health, CRC Press, Boca Raton, FL, in press.
[8] Belyaev, I., 2005. Non-thermal biological effects of microwaves. Microwave Rev. 11, 13- 29.
[9] Belyaev, I., 2015. Biophysical mechanisms for nonthermal microwave effects. In: Markov M.S. (Ed), Electromagnetic Fields in Biology and Medicine, CRC Press, New York, pp 49-67. [10] Panagopoulos, D. J., Johansson, O., Carlo, G. L., 2015. Polarization: a key difference between man-made and natural electromagnetic fields, in regard to biological activity. Sci. Rep. 2015 Oct 12;5:14914. doi: 10.1038/srep14914.
[11] Pall ML. 2018 Wi-Fi is an important threat to human health. Environ Res 164:405-416. doi: 10.1016/j.envres.2018.01.035.
[12] Pilla, A. A., 2012. Electromagnetic fields instantaneously modulate nitric oxide signaling in challenged biological systems. Biochem. Biophys. Res. Commun. 28, 426:330-333. doi: 10.1016/j.bbrc.2012.08.078.
[13] Lu, X. W., Du, L., Kou, L., Song, N., Zhang, Y. J., Wu, M. K., Shen, J. F., 2015. Effects of
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moderate static magnetic fields on the voltage-gated sodium and calcium channels currents in trigeminal ganglion neurons. Electromagn. Biol. Med. 34, 285-292. doi: 10.3109/15368378.2014.906448.
[14] Tabor, K. M., Bergeron, S. A., Horstick, E. J., Jordan, D. C., Aho, V., Porkka-Heiskanen, T., Haspel, G, Burgess, H. A., 2014. Direct activation of the Mauthner cell by electric field pulses drives ultrarapid escape responses. J Neurophysiol 112:834-844. doi: 10.1152/jn.00228.2014.
[15] Zhang, J., Li, M., Kang, E. T., Neoh, K. G., 2016. Electrical stimulation of adipose-derived mesenchymal stem cells in conductive scaffolds and the roles of voltage-gated ion channels.
Acta Biomater. 32, 46-56. doi: 10.1016/j.actbio.2015.12.024.
[16] Tekieh T, Sasanpour P, Rafii-Tabar H. 2016 Effects of electromagnetic field exposure on conduction and concentration of voltage gated calcium channels: A Brownian dynamics study. Brain Res 1646:560-569.
[17] ICNIRP 2009 International Commission on Non-ionizing Radiation Protection. ICNIRP statement on the “Guidelines for limiting exposure to time-varying electric, magnetic and electromagnetic fields (up to 300 GHz). Health Phys 97:257-258.
[18] Bioinitiative Working Group. 2007 BioInitiative Report: A rationale for biologically- based public exposure standard for electromagnetic fields (ELF and RF). Sage C and Carpenter DO (Eds.), Available online: https://ift.tt/1EM61Gq (accessed March 19, 2018)
[19] Sypniewska, R. K., Millenbaugh, N. J., Kiel, J. L., Blystone, R. V., Ringham, H. N., Mason, P. A., Witzmann, F. A., 2010. Protein changes in macrophages induced by plasma from rats exposed to 35 GHz millimeter waves. Bioelectromagnetics 3, 656-663. doi: 0.1002/bem.20598. [20] Kalns, J., Ryan, K. L., Mason, P. A., Bruno, J. G., Gooden, R., Kiel, J. L., 2000. Oxidative stress precedes circulatory failure induced by 35-GHz microwave heating. Shock 13, 52-59.
[21] Garbuz, D. G., 2017. Regulation of heat shock gene expression in response to stress. Mol. Biol. 51, 352-367. doi: 10.1134/S0026893317020108.
[22] Park, H. K., Lee, J. E., Lim, J. F., Kang, B. H., 2014. Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from the mitochondria to the ER in cancer cells. Mol. Cancer 13 Article Number: 148 doi: 10.1186/1476-4598-13-148.
[23] Krebs, J., Groenendyk, J., Michalek, M., 2011. Ca2+-signaling, alternative splicing and endoplasmic reticulum stress responses. Neurochem. Res. 36, 1198-1211. doi: 10.1007/s11064- 011-0431-4.
[24] Pilla, A. A., 2013. Nonthermal electromagnetic fields: from first messenger to therapeutic applications. Electromagn Biol Med 32, 123-136. doi: 10.3109/15368378.2013.776335.
[25] Pall, M. L., 2014. Electromagnetic field activation of voltage-gated calcium channels: role in therapeutic effects. Electromagn. Biol. Med. 2014 Apr 8 doi: 10.3109/15368378.2014.906447. [26] Raines JK. 1981. Electromagnetic Field Interactions with the Human Body: Observed Effects and Theories. Greenbelt, Maryland: National Aeronautics and Space Administration 1981; 116 p.
[27] Goldsmith JR. 1997 Epidemiologic evidence relevant to radar (microwave) effects. Env Health Perspect 105(Suppl 6):1579-1587.
[28] Hecht Karl. 2016 Health Implications of Long-Term Exposures to Electrosmog. Brochure 6 of A Brochure Series of the Competence Initiative for the Protection of Humanity, the Environment and Democracy. https://ift.tt/2ttadKT content/uploads/2016/07/KI_Brochure-6_K_Hecht_web.pdf (accessed Feb. 11, 2018)
[29] Marha K. 1966 Biological Effects of High-Frequency Electromagnetic Fields (Translation). ATD Report 66-92. July 13, 1966 (ATD Work Assignment No. 78, Task 11). [30] Glaser ZR, PhD. 1971 Naval Medical Research Institute Research Report, June 1971. Bibliography of Reported Biological Phenomena (“Effects”) and Clinical Manifestations Attributed to Microwave and Radio-Frequency Radiation. Report No. 2 Revised.
[14] Tabor, K. M., Bergeron, S. A., Horstick, E. J., Jordan, D. C., Aho, V., Porkka-Heiskanen, T., Haspel, G, Burgess, H. A., 2014. Direct activation of the Mauthner cell by electric field pulses drives ultrarapid escape responses. J Neurophysiol 112:834-844. doi: 10.1152/jn.00228.2014.
[15] Zhang, J., Li, M., Kang, E. T., Neoh, K. G., 2016. Electrical stimulation of adipose-derived mesenchymal stem cells in conductive scaffolds and the roles of voltage-gated ion channels.
Acta Biomater. 32, 46-56. doi: 10.1016/j.actbio.2015.12.024.
[16] Tekieh T, Sasanpour P, Rafii-Tabar H. 2016 Effects of electromagnetic field exposure on conduction and concentration of voltage gated calcium channels: A Brownian dynamics study. Brain Res 1646:560-569.
[17] ICNIRP 2009 International Commission on Non-ionizing Radiation Protection. ICNIRP statement on the “Guidelines for limiting exposure to time-varying electric, magnetic and electromagnetic fields (up to 300 GHz). Health Phys 97:257-258.
[18] Bioinitiative Working Group. 2007 BioInitiative Report: A rationale for biologically- based public exposure standard for electromagnetic fields (ELF and RF). Sage C and Carpenter DO (Eds.), Available online: https://ift.tt/1EM61Gq (accessed March 19, 2018)
[19] Sypniewska, R. K., Millenbaugh, N. J., Kiel, J. L., Blystone, R. V., Ringham, H. N., Mason, P. A., Witzmann, F. A., 2010. Protein changes in macrophages induced by plasma from rats exposed to 35 GHz millimeter waves. Bioelectromagnetics 3, 656-663. doi: 0.1002/bem.20598. [20] Kalns, J., Ryan, K. L., Mason, P. A., Bruno, J. G., Gooden, R., Kiel, J. L., 2000. Oxidative stress precedes circulatory failure induced by 35-GHz microwave heating. Shock 13, 52-59.
[21] Garbuz, D. G., 2017. Regulation of heat shock gene expression in response to stress. Mol. Biol. 51, 352-367. doi: 10.1134/S0026893317020108.
[22] Park, H. K., Lee, J. E., Lim, J. F., Kang, B. H., 2014. Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from the mitochondria to the ER in cancer cells. Mol. Cancer 13 Article Number: 148 doi: 10.1186/1476-4598-13-148.
[23] Krebs, J., Groenendyk, J., Michalek, M., 2011. Ca2+-signaling, alternative splicing and endoplasmic reticulum stress responses. Neurochem. Res. 36, 1198-1211. doi: 10.1007/s11064- 011-0431-4.
[24] Pilla, A. A., 2013. Nonthermal electromagnetic fields: from first messenger to therapeutic applications. Electromagn Biol Med 32, 123-136. doi: 10.3109/15368378.2013.776335.
[25] Pall, M. L., 2014. Electromagnetic field activation of voltage-gated calcium channels: role in therapeutic effects. Electromagn. Biol. Med. 2014 Apr 8 doi: 10.3109/15368378.2014.906447. [26] Raines JK. 1981. Electromagnetic Field Interactions with the Human Body: Observed Effects and Theories. Greenbelt, Maryland: National Aeronautics and Space Administration 1981; 116 p.
[27] Goldsmith JR. 1997 Epidemiologic evidence relevant to radar (microwave) effects. Env Health Perspect 105(Suppl 6):1579-1587.
[28] Hecht Karl. 2016 Health Implications of Long-Term Exposures to Electrosmog. Brochure 6 of A Brochure Series of the Competence Initiative for the Protection of Humanity, the Environment and Democracy. https://ift.tt/2ttadKT content/uploads/2016/07/KI_Brochure-6_K_Hecht_web.pdf (accessed Feb. 11, 2018)
[29] Marha K. 1966 Biological Effects of High-Frequency Electromagnetic Fields (Translation). ATD Report 66-92. July 13, 1966 (ATD Work Assignment No. 78, Task 11). [30] Glaser ZR, PhD. 1971 Naval Medical Research Institute Research Report, June 1971. Bibliography of Reported Biological Phenomena (“Effects”) and Clinical Manifestations Attributed to Microwave and Radio-Frequency Radiation. Report No. 2 Revised.
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https://ift.tt/2Mlbw5x frequency+1972&btnG=&hl=en&as_sdt=0%2C38 (Accessed Sept. 9, 2017)
[31] Bise W. 1978 Low power radio-frequency and microwave effects on human electroencephalogram and behavior. Physiol Chem Phys 10:387-398.
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[40] Pall ML. 2013 The NO/ONOO- cycle as the central cause of heart failure. Int J Mol Sci 14:22274-22330. doi: 10.3390/ijms141122274.
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[32] Belyaev I, Dean A, Eger H, Hubmann G, Jandrisovits R, Kern M, Kundi M, Moshammer H, Lercher P, Müller K, Oberfeld G, Ohnsorge P, Pelzmann P, Scheingraber C, Thill R. 2016 EUROPAEM EMF Guideline 2016 for the prevention, diagnosis and treatment of EMF-related health problems and illnesses. Rev Environ Health DOI 10.1515/reveh-2016-0011.j
[33] Hedendahl L, Carlberg M, Hardell L. 2015 Electromagnetic hypersensitivity--an increasing challenge to the medical profession. Rev Environ Health 30:209-215. doi: 10.1515/reveh-2015- 0012.
[34] Carpenter DO. 2015 The microwave syndrome or electro-hypersensitivity: historical background. Rev Environ Health 30:217-222. doi: 10.1515/reveh-2015-0016
[34] Havas M. 2013 Radiation from wireless technology affects the blood, the heart and the autonomic nervous system. Rev Environ Health 82:75-84.https://ift.tt/2MkCM49 0004
[35] Havas M, Marrongelle J, Pollmer, Kelley E, Rees C, Tully S. 2010 Provocation study using heart rate variability shows microwave radiation from 2.4 GHz cordless phone affects autonomic nervous system. Eur J Oncol 5:273-300.
[36] Gordon, ZV. 1966 [Problems of industrial hygiene and biological effects of super high frequency electromagne c fields.] Medizina, Moscow (in Russian)
[37] Presman, AS. Electromagnetic fields and life. New York: Plenum Press, 1970.
[38] Tolgskaya MS, Gordon ZV. 1973. Pathological Effects of Radio Waves, Translated from Russian by B Haigh. Consultants Bureau, New York/London, 146 pages.
[39] Siebert DM, Drezner JA. 2018 Sudden cardiac arrest on the field of play: turning tragedy into a survivable event. Neth Heart J 26:115-119. doi: 10.1007/s12471-018-1084-6.
[40] Pall ML. 2013 The NO/ONOO- cycle as the central cause of heart failure. Int J Mol Sci 14:22274-22330. doi: 10.3390/ijms141122274.
[41] Liu YQ, Gao YB, Dong J, Yao BW, Zhao L, Peng RY. 2015 Pathological changes in the sinoatrial node tissues of rats caused by pulsed microwave exposure. Biomed Environ Sci 28:72- 75. doi: 10.3967/bes2015.007.
[42] Pritchard C, Mayers A, Baldwin D. 2013 Changing patterns of neurological mortality in the 10 major developed countries--1979-2010. Public Health 127:357-368. doi: 10.1016/j.puhe.2012.12.018.
[43] Pritchard C, Rosenorn-Lanng E. 2015 Neurological deaths of American adults (55-74) and the over 75's by sex compared with 20 Western countries 1989-2010: Cause for concern. Surg Neurol Int 2015 Jul 23;6:123. doi: 10.4103/2152-7806.161420.
[44] Vieira RT, Caixeta L, Machado S, Silva AC, Nardi AE, Arias-Carrión O, Carta MG. 2013 Epidemiology of early-onset dementia: a review of the literature. Clin Pract Epidemiol Ment Health 9:88-95. doi: 10.2174/1745017901309010088.
[45] Hallberg O, Johansson O. 2005 Alzheimer mortality—why does it increase so rapidly in sparsely populated areas? Eur Biol Bioelectromag 1;1-8
[46] [Dossey L. 2014 FOMO, digital dementia, and our dangerous experiment. Explore (NY) 2014 Mar-Apr;10(:69-73. doi: 10.1016/j.explore.2013.12.008.
[47] Moledina S, Khoja A. 2018 Letter to the Editor: Digital Dementia-Is Smart Technology Making Us Dumb? Ochsner J. 2018 Spring;18(1):12.
[48] Spitzer, Manfred. Digitale Demenz. Wie wir uns und unsere Kinder um den Verstand bringen. Droemer Verlag, Munich 2012.
[49] Mattson MP. 2007 Calcium and neurodegeneration. Aging Cell 6:337-350. doi: 10.1111/j.1474-9726.2007.00275.x
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[50] Celsi F, Pizzo P, Brini M, Leo S, Fotino C, Pinton P, Rizzuto R. 2009 Mitochondria, calcium and cell death: a deadly triad in neurodegeneration. Biochim Biophys Acta 1787:335- 344. doi: 10.1016/j.bbabio.2009.02.021.
[51] Carreiras MC, Mendes E, Perry MJ, Francisco AP, Marco-Contelles J. 2013 The multifactorial nature of Alzheimer's disease for developing potential therapeutics. Curr Top Med Chem 13:1745-1770.
[52] Jiang DP, Li J, Zhang J, Xu SL, Kuang F, Lang HY, Wang YF, An GZ, Li JH, Guo GZ. 2013 Electromagnetic pulse exposure induces overexpression of beta amyloid protein in rats. Arch Med Res 44:178-184. doi: 10.1016/j.arcmed.2013.03.005.
[53] Jiang DP, Li JH, Zhang J, Xu SL, Kuang F, Lang HY, Wang YF, An GZ, Li J, Guo GZ. 2016 Long-term electromagnetic pulse exposure induces Abeta deposition and cognitive dysfunction through oxidative stress and overexpression of APP and BACE1. Brain Res. 2016 Jul 1;1642:10-19. doi: 10.1016/j.brainres.2016.02.053.
[54] Dasdag S, Akdag MZ, Kizil G, Kizil M, Cakir DU, Yokus B. 2012 Effect of 900 MHz radio frequency radiation on beta amyloid protein, protein carbonyl, and malondialdehyde in the brain. Electromagn Biol Med. 2012 Mar;31(1):67-74. doi: 10.3109/15368378.2011.624654.
[55] Dasdag S, Akdag MZ, Erdal ME, Erdal N, Ay OI, Ay ME, Yilmaz SG, Tasdelen B, Yegin K. 2015 Long term and excessive use of 900 MHz radiofrequency radiation alter microRNA expression in brain. Int J Radiat Biol 91:306-311. doi: 10.3109/09553002.2015.997896.
[56] Arendash GW, Mori T, Dorsey M, Gonzalez R, Tajiri N, Borlongan C. 2012 Electromagnetic treatment to old Alzheimer's mice reverses β-amyloid deposition, modifies cerebral blood flow, and provides selected cognitive benefit. PLoS One. 2012;7(4):e35751. doi: 10.1371/journal.pone.0035751.
[57] Arendash GW. 2016 Review of the Evidence that Transcranial Electromagnetic Treatment will be a Safe and Effective Therapeutic Against Alzheimer's Disease. J Alzheimers Dis 53:753- 771.
[58] García AM, Sisternas A, Hoyos SP. 2008 Occupational exposure to extremely low frequency electric and magnetic fields and Alzheimer disease: a meta-analysis. Int J Epidemiol 37:329-340. doi: 10.1093/ije/dym295.
[59] Hug K1, Röösli M, Rapp R. 2006 Magnetic field exposure and neurodegenerative diseases--recent epidemiological studies. Soz Praventivmed 51:210-220.
[59A] No author listed. 1997 Stronger evidence for an Alzheimer’s EMF connection. Microwave News XVII, Jan/Feb 1997, 1,6,7.
[60] Gandhi OP, Kang G. 2001 Calculation of induced current densities for humans by magnetic fields from electronic article surveillance devices. Phys Med Biol 46:2759-2771.
[61] Gandhi OP, Morgan LL, de Salles AA, Han YY, Herberman RB, Davis DL. 2012 Exposure Limits: The underestimation of absorbed cell phone radiation, especially in children. Electromagn Biol Med 31:34-51. doi: 10.3109/15368378.2011.622827.
[62] Belyaev IY, Markovà E, Hillert L, Malmgren LO, Persson BR. 2009 Microwaves from UMTS/GSM mobile phones induce long-lasting inhibition of 53BP1/gamma-H2AX DNA repair foci in human lymphocytes. Bioelectromagnetics 30:129-141. doi: 10.1002/bem.20445.
[63] Markovà E, Malmgren LO, Belyaev IY. 2010 Microwaves from Mobile Phones Inhibit 53BP1 Focus Formation in Human Stem Cells More Strongly Than in Differentiated Cells: Possible Mechanistic Link to Cancer Risk. Environ Health Perspect 118:394-399. doi: 10.1289/ehp.0900781
[64] Lee SS, Kim HR, Kim MS, Park SH, Kim DW. 2014 Influence of smart phone Wi-Fi signals on adipose-derived stem cells. Ja J Cranofac Surg 25:1902-1907. doi: 10.1097/SCS.0000000000000939.
[65] Czyz J, Guan K, Zeng Q, Nikolova T, Meister A, Schönborn F, Schuderer J, Kuster N, Wobus AM. 2004 High frequency electromagnetic fields (GSM signals) affect gene expression
[51] Carreiras MC, Mendes E, Perry MJ, Francisco AP, Marco-Contelles J. 2013 The multifactorial nature of Alzheimer's disease for developing potential therapeutics. Curr Top Med Chem 13:1745-1770.
[52] Jiang DP, Li J, Zhang J, Xu SL, Kuang F, Lang HY, Wang YF, An GZ, Li JH, Guo GZ. 2013 Electromagnetic pulse exposure induces overexpression of beta amyloid protein in rats. Arch Med Res 44:178-184. doi: 10.1016/j.arcmed.2013.03.005.
[53] Jiang DP, Li JH, Zhang J, Xu SL, Kuang F, Lang HY, Wang YF, An GZ, Li J, Guo GZ. 2016 Long-term electromagnetic pulse exposure induces Abeta deposition and cognitive dysfunction through oxidative stress and overexpression of APP and BACE1. Brain Res. 2016 Jul 1;1642:10-19. doi: 10.1016/j.brainres.2016.02.053.
[54] Dasdag S, Akdag MZ, Kizil G, Kizil M, Cakir DU, Yokus B. 2012 Effect of 900 MHz radio frequency radiation on beta amyloid protein, protein carbonyl, and malondialdehyde in the brain. Electromagn Biol Med. 2012 Mar;31(1):67-74. doi: 10.3109/15368378.2011.624654.
[55] Dasdag S, Akdag MZ, Erdal ME, Erdal N, Ay OI, Ay ME, Yilmaz SG, Tasdelen B, Yegin K. 2015 Long term and excessive use of 900 MHz radiofrequency radiation alter microRNA expression in brain. Int J Radiat Biol 91:306-311. doi: 10.3109/09553002.2015.997896.
[56] Arendash GW, Mori T, Dorsey M, Gonzalez R, Tajiri N, Borlongan C. 2012 Electromagnetic treatment to old Alzheimer's mice reverses β-amyloid deposition, modifies cerebral blood flow, and provides selected cognitive benefit. PLoS One. 2012;7(4):e35751. doi: 10.1371/journal.pone.0035751.
[57] Arendash GW. 2016 Review of the Evidence that Transcranial Electromagnetic Treatment will be a Safe and Effective Therapeutic Against Alzheimer's Disease. J Alzheimers Dis 53:753- 771.
[58] García AM, Sisternas A, Hoyos SP. 2008 Occupational exposure to extremely low frequency electric and magnetic fields and Alzheimer disease: a meta-analysis. Int J Epidemiol 37:329-340. doi: 10.1093/ije/dym295.
[59] Hug K1, Röösli M, Rapp R. 2006 Magnetic field exposure and neurodegenerative diseases--recent epidemiological studies. Soz Praventivmed 51:210-220.
[59A] No author listed. 1997 Stronger evidence for an Alzheimer’s EMF connection. Microwave News XVII, Jan/Feb 1997, 1,6,7.
[60] Gandhi OP, Kang G. 2001 Calculation of induced current densities for humans by magnetic fields from electronic article surveillance devices. Phys Med Biol 46:2759-2771.
[61] Gandhi OP, Morgan LL, de Salles AA, Han YY, Herberman RB, Davis DL. 2012 Exposure Limits: The underestimation of absorbed cell phone radiation, especially in children. Electromagn Biol Med 31:34-51. doi: 10.3109/15368378.2011.622827.
[62] Belyaev IY, Markovà E, Hillert L, Malmgren LO, Persson BR. 2009 Microwaves from UMTS/GSM mobile phones induce long-lasting inhibition of 53BP1/gamma-H2AX DNA repair foci in human lymphocytes. Bioelectromagnetics 30:129-141. doi: 10.1002/bem.20445.
[63] Markovà E, Malmgren LO, Belyaev IY. 2010 Microwaves from Mobile Phones Inhibit 53BP1 Focus Formation in Human Stem Cells More Strongly Than in Differentiated Cells: Possible Mechanistic Link to Cancer Risk. Environ Health Perspect 118:394-399. doi: 10.1289/ehp.0900781
[64] Lee SS, Kim HR, Kim MS, Park SH, Kim DW. 2014 Influence of smart phone Wi-Fi signals on adipose-derived stem cells. Ja J Cranofac Surg 25:1902-1907. doi: 10.1097/SCS.0000000000000939.
[65] Czyz J, Guan K, Zeng Q, Nikolova T, Meister A, Schönborn F, Schuderer J, Kuster N, Wobus AM. 2004 High frequency electromagnetic fields (GSM signals) affect gene expression
85
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[71] Bhargav H, Srinivasan TM, Varambally S, Gangadhar BN, Koka P. 2015 Effect of Mobile Phone-Induced Electromagnetic Field on Brain Hemodynamics and Human Stem Cell Functioning: Possible Mechanistic Link to Cancer Risk and Early Diagnostic Value of Electronphotonic Imaging. J Stem Cells 10 (4): 287-294.
[72] Redmayne M, Johansson O. 2015 Radiofrequency exposure in young and old: different sensitivities in the light of age-relevant natural differences. Rev Environ Health 30: 323-335. doi: 10.1515/reveh-2015-0030.
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[74] Speit G, Gminski R, Tauber R. 2013 Genotoxic effects of exposure to radiofrequency electromagnetic fields (RF-EMF) in HL-60 cells are not reproducible. Mutat Res Genet Toxicol Environ Mutagen 755: 163-166.
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[78] Khurana VG, Teo C, Kundi M, Hardell L, Carlberg M. 2009 Cell phones and brain tumors: a review including the long-term epidemiologic data. Surg Neurol 72:205-214.
[79] Desai NR, Kesari KK, Agarwal A. 2009 Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on the male reproductive system. Reproduct Biol Endocrinol 7:114.
[80] Makker K, Varghese A, Desai NR, Mouradi R, Agarwal A. 2009 Cell phones: modern man's nemesis? Reprod Biomed Online 18:148-157.
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[66] XuF,BaiQ,ZhouK,MaL,DuanJ,ZhuangF,XieC,LiW,ZouP,ZhuC. 2016 Age- dependent acute interference with stem and progenitor cell proliferation in the hippocampus after exposure to 1800 MHz electromagnetic radiation. Electromagn Biol Med 3:1-9. doi: 10.1080/15368378.2016.
[67] Odaci E, Bas O, Kaplan S. 2008 Effects of prenatal exposure to a 900 MHz electromagnetic field on the dentate gyrus of rats: a stereological and histopathological study. Brain Res 1238:224-229. doi: 10.1016/j.brainres.2008.08.013.
[68] Uchugonova A, Isemann A, Gorjup E, Tempea G, Bückle R, Watanabe W, König K. 2008 Optical knock out of stem cells with extremely ultrashort femtosecond laser pulses. J Biophotonics 1(6):463-469. doi: 10.1002/jbio.200810047.
[69] WangC,WangX,ZhouH,DongG,GuanX,WangL,XuX,WangS,ChenP,PengR,Hu X. 2015 Effects of pulsed 2.856 GHz microwave exposure on BM-MSCs isolated from C57BL/6 mice. PLoS One. 2015 Feb 6;10(2):e0117550. doi: 10.1371/journal.pone.0117550. [70] Teven CM, Greives M, Natale RB, Su Y, Luo Q, He BC, Shenaq D, He TC, Reid RR. 2012 Differentiation of osteoprogenitor cells is induced by high-frequency pulsed electromagnetic fields. J Craniofac Surg 23:586-593. doi: 10.1097/SCS.0b013e31824cd6de.
[71] Bhargav H, Srinivasan TM, Varambally S, Gangadhar BN, Koka P. 2015 Effect of Mobile Phone-Induced Electromagnetic Field on Brain Hemodynamics and Human Stem Cell Functioning: Possible Mechanistic Link to Cancer Risk and Early Diagnostic Value of Electronphotonic Imaging. J Stem Cells 10 (4): 287-294.
[72] Redmayne M, Johansson O. 2015 Radiofrequency exposure in young and old: different sensitivities in the light of age-relevant natural differences. Rev Environ Health 30: 323-335. doi: 10.1515/reveh-2015-0030.
[73] SCENIHR, 2015. Health effects of EMF – 2015 Scientific Committee on Emerging and Newly Identified Health Risks SCENIHR: opinion on potential health effects of exposure to electromagnetic fields (EMF). https://ift.tt/2yTtkxr (accessed Sept. 7, 2017)
[74] Speit G, Gminski R, Tauber R. 2013 Genotoxic effects of exposure to radiofrequency electromagnetic fields (RF-EMF) in HL-60 cells are not reproducible. Mutat Res Genet Toxicol Environ Mutagen 755: 163-166.
{75] Schwarz C, Kratochvil E, Pilger A, Kuster N, Adlkofer F, Rüdiger HW. 2008 Radiofrequency electromagnetic fields (UMTS, 1,950 MHz) induce genotoxic effects in vitro in human fibroblasts but not in lymphocytes. Int Arch Occup Environ Health 81: 755-767.
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[79] Desai NR, Kesari KK, Agarwal A. 2009 Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on the male reproductive system. Reproduct Biol Endocrinol 7:114.
[80] Makker K, Varghese A, Desai NR, Mouradi R, Agarwal A. 2009 Cell phones: modern man's nemesis? Reprod Biomed Online 18:148-157.
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[85] Carpenter DO. 2010 Electromagnetic fields and cancer: the cost of doing nothing. Rev Environ Health 25:75-80.
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90
Thus Article Chapter 7: The Great Risks of 5G: What We Know and What We Don’t Know
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