Drug Cocktail for Newly Diagnose GBM - Hallo friendsTOP POLENNEWS, In the article you read this time with the title Drug Cocktail for Newly Diagnose GBM, We have prepared this article for you to read and retrieve information therein. Hopefully the contents of postings Article cultur, Article economic, Article health, Article news, Article politique, Article sport, We write this you can understand. Alright, good read.

Title : Drug Cocktail for Newly Diagnose GBM
link : Drug Cocktail for Newly Diagnose GBM

Drug Cocktail for Newly Diagnose GBM

Hi Everyone,

I'm new to the blog and blogging in general. My brother is 3 weeks post op craniotomy for removal of 2cm brain tumor in left frontal lobe - complete resection was not possible but approximately 80% removed. Otherwise Joe is a healthy 35 yo male

Pathology report came back:
Grade IV Glioblastoma, wild type
Negative IDH1/2
Negative MGMT methylation
No amplification of EGFR gene

He will be part of a clinical trial with proton therapy radiation at MGH in Boston.  Joe is gripped by depression but committed to starting treatment - hopefully along with a drug cocktail. I've been helping him research and pull it together. When he starts radiation and chemo in a week or so I would like him to be on below meds / supplements

Drug	Dosage
Valproic Acid	1000mg
Chloroquine	250mg daily
Celebrex	200-400mg daily
Fluoxetine	40mg daily

Supplement	Dose
Medical Grade Cannabis
Boshwella	1000mg
Green Tea
Curcumin	1000-2000mg +
Melatonin	10-20mg
Maitake D	100mg
Fish Oil
Probiotic
Turkey Tail - ie PSK	3000mg
Vitamin D3	5000-10,000 UI
quercetin	500mg
milk thistle	1000-2000mg
Reishi mushroom

This is not a complete outline as I'm using some supplements he purchased and some meds he is already on (valproic acid).  I would love to have any suggestions or thoughts.

I also have some questions for you all (I'm sure the first of many) 

1. How open are neuro oncologist to a cocktail approach? Joe is afraid of asking them about adding anything to the current standard of care 

2. Is it true that unmethylated MGMT tumors are not as responsive to TMZ? Should we ask about a metronomic everyday low dose? What is the current dosing of TMZ in standard of care?

3. Should we look into adding Antabuse, Metformin, or an ACE Inhibitor? 

Best, 

Jenna

*my apologies for any typos 

Thus Article Drug Cocktail for Newly Diagnose GBM

That's an article Drug Cocktail for Newly Diagnose GBM This time, hopefully can give benefits to all of you. well, see you in posting other articles.

You are now reading the article Drug Cocktail for Newly Diagnose GBM with the link address https://polennews.blogspot.com/2018/09/drug-cocktail-for-newly-diagnose-gbm.html

Tweet

Subscribe to receive free email updates: