Increased expression of androgen receptor (AR) in GBM. Enzalutamide (androgen receptor inhibitor) - Hallo friendsTOP POLENNEWS, In the article you read this time with the title Increased expression of androgen receptor (AR) in GBM. Enzalutamide (androgen receptor inhibitor), We have prepared this article for you to read and retrieve information therein. Hopefully the contents of postings Article cultur, Article economic, Article health, Article news, Article politique, Article sport, We write this you can understand. Alright, good read.

Title : Increased expression of androgen receptor (AR) in GBM. Enzalutamide (androgen receptor inhibitor)
link : Increased expression of androgen receptor (AR) in GBM. Enzalutamide (androgen receptor inhibitor)

Increased expression of androgen receptor (AR) in GBM. Enzalutamide (androgen receptor inhibitor)

SNO 2016 abstract: CSIG-13 ANDROGEN RECEPTOR IS INVOLVED IN GLIOBLASTOMA AND PRESENTS A POTENTIAL THERAPEUTIC TARGET

SNO 2017 abstract: CSIG-24. ANDROGEN RECEPTOR IS A POTENTIAL THERAPEUTIC TARGET IN GLIOBLASTOMA

"Enzalutamide given orally (20 mg/kg three time per week) to nude mice bearing human gliomas (U78MG) resulted in reduction of 72% in tumor volume (p=0.0027) as compared to mice treated with vehicle. We hope that the results of this study together with continued laboratory efforts will lead to a new approach for the treatment of human glioblastoma."

Enzalutamide is an androgen receptor inhibitor approved by the FDA in 2012 for treatment of prostate cancer.

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