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Title : Olaparib + radiation for recurrent glioma?
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Olaparib + radiation for recurrent glioma?

Hello all,

My sister is currently preparing for treatments after a successful surgery. She has recurrent IDH1mut, MGMT methylated astrocytoma, previously grade 3, we're still waiting for pathology report from the latest surgery. Preliminary treatment plan is to have radiation therapy (recurrence is outside of the original tumor location) and then continue with CCNU.

I found this one study (Paradigm-trial) that studies olaparib in combination with RT.
Do you think it would be worth a try? This could be possible for us financially since the RT last only about a month so cost of olaparib would be reasonable.

Br,
Juha

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