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Title : DNX-201 With Pembrolizumab (Keptruda)
link : DNX-201 With Pembrolizumab (Keptruda)

DNX-201 With Pembrolizumab (Keptruda)

Hello All,

I am looking for any comments, experience and suggestions with the DNX-2401 trial.

The Phase II just opened and I am enrolled for the procedure on Monday.

My GBM was resected in June 2015 and there has been some mass increases in the area between my cavity and skull.  Shows some signs of tumor and some signs as necrosis.


Of the couple of trial options offered to me, (southern California) these seems like the best, like the biopsy aspect of this trial.

When I asked a GBM research scientist friend of mine, I got the following comment:

Paraphased:

 - DNX-2401 is a one shot try.  If it comes back up the biopsy hole, then nothing is going to happen.

So this makes sense, that if no DNX-201 then nothing for the PD1 to work on.

But is this really a concern?

Any, why cannot you just re-inject if this happens?

Marc

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